Johnson Francis
Department of Cardiology,
Baby Memorial Hospital.
(Former Professor of Cardiology, Govt. Medical College, Kozhikode)
Abstract
Initial description of Brugada syndrome in 1992 was that of syncopal episodes and/or sudden death in persons with structurally normal heart and a characteristic ECG pattern of right bundle branch block with ST segment elevation in leads V1 to V3 . Sometimes individuals with a diagnostic ECG may be totally asymptomatic and may be having a family history of sudden death. Genetic nature of the disorder and mutation in sodium channel gene SCN5A was described in 1998.
