A Case Of Unexplained Dyspnoea
Abstract
Myasthenia gravis is a neuromuscular disease caused by circulating antibodies that block  acetylcholine receptors at the post synaptic neuromuscular junction, characterized by fluctuating muscle weakness and fatigue. Shortness of breath is an uncommon initial presentation of myasthenia gravis. We report a case of undiagnosed myasthenia gravis, where patient initially presented with episodic shortness of breath.This report highlights the need to consider myasthenia gravis in the differential diagnosis of an otherwise unexplained dyspnea.References
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2. Oosterhuis HJ. The natural course of myasthenia gravis: a long term follow up study. J Neurol Neurosurg Psychiatry 1989; 52:1121.
3. .H Vaidya Unusual presentation of myasthenia gravis with acute respiratory failure in the emergency roomEmerg Med J 2006;23:410–413. doi: 10.1136/emj.2005.030429
4. Oh SJ, Kim DE, Kuruoglu R, et al. Diagnostic sensitivity of the laboratory tests in myasthenia gravis. Muscle Nerve 1992; 15:720.
5. Vincent A, McConville J, Farrugia ME, et al. Antibodies in myasthenia gravis and related disorders. Ann N Y Acad Sci 2003; 998:324.
