Anti GAD65 Encephalopathy Presenting with Reversible Encephalopathy and Orofacial Dyskinesias
Authors
Mohan Leslie Noone
Department of Neurology,
Baby Memorial Hospital.
Abstract
Anti GAD65 antibodies have been implicated predominantly in limbic encephalitis in addition to systemic disorders like Type 1 diabetes mellitus. Here a patient presenting with seizures, behavior disturbances, memory and gait abnormalities and peculiar orofacial dyskinesias is reported, who was found to have high titre positivity of Anti-GAD 65 and excellent therapeutic response to steroids, suggesting that this could be an additional phenotype for the encephalopathy caused by this antibody.