Grinspan's Syndrome

Abstract

Grinspan's syndrome (GS) is characterized by the triad of oral lichen planus (OLP), diabetes mellitus and hypertension. Certain drugs which are used in the treatment of diabetes and hypertension can produce lichenoid reactions of the oral mucosa. The patient being reported is a  middle aged lady suffering from recurrent OLP. She is a diabetic and hypertensive. Initially, she had uncontrolled blood glucose levels and had recurrent OLP. But even after controlling her blood glucose levels, she continued to have OLP, with increased frequency. On the basis of her medical history and clinical features, she was diagnosed to have GS. Her routine antidiabetic and antihypertensive medications were modified, following which her OLP showed resolution. Since GS can be drug induced, a detailed medication history is essential in all cases of OLP.