Pheochromocytoma: State of the Art and Guide to Evaluation and Management
Abstract
Pheochromocytoma though rare is an important cause of secondary hypertension. Detection of such a tumor should lead the clinician to look associated familial syndromes like MEN, PGL, NF, VHL etc. Appropriate biochemical evaluation taking necessary precautions to avoid the false positive and negative results associated with improper sample collection has to be avoided. Once biochemically localized, radiological imaging like CECT is used to localize the tumor.Surgical removal should be attempted only after adequate pre operative preparation. Laparoscopic adrenalectomy is the goldstandard  Experienced anesthesiologist is critical to the outcome in the operating room. Aggressive post operative management of the hypotension is critical to patient recoveryReferences
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James C Ulchaker, David A Goldfarb, Emanuel A Bravo, Andrew C Novick, Successful outcomes in Pheochromocytoma surgery in the modern era. Journal of Urology Vol 161, 764-767, 1999
David S Goldstein , Graeme Eisenhofer, John Flynn et al. Diagnosis and localization of Pheochromocytoma. Hypertension May 2004, 907-910.
Emmanuel L. Bravo. Pheochromocytoma: Current perspectives in pathogenesis, diagnosis and management. Arq Bras Endocrinol Metab 2004; 48/5: 746-750.
Micheal Gagner. Laparoscopic adrenalectomy, Textbook of Endocrine surgery. WB Saunders company 1997, 535-545
Richard A Prinz, Mark E Falimirski. Operative approaches to the adrenal gland. WB Saunders company 1997, 529-535
Lenders JW, Pacak K, Walther MM, et al. Biochemical diagnosis of pheochromocytoma: which test is best? JAMA 2002; 287: 1427–34.
