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Dr. Shinto Francis Thekkudan
Senior Consultant & Chief
Tab 1
Dr. Shinto Francis Thekkudan MD (General Medicine), DM (Clinical Hematology), Fellowship in Bone Marrow Transplant
Senior Consultant & Chief
Dr. Shinto is a highly accomplished clinician with a robust background in clinical medicine and advanced training in hematology. After earning an MD in Clinical Medicine, Dr. Shinto pursued a Doctorate (DM) in Clinical Hematology at the prestigious Sanjay Gandhi Post Graduate Institute (SGPGI), Lucknow. Subsequently, he gained extensive experience at leading institutions such as Christian Medical College (CMC), Vellore, where he served as Registrar in Clinical Hematology, and Rajiv Gandhi Cancer Institute (RGCI), New Delhi, where he completed a fellowship in Bone Marrow Transplantation (BMT).
Dr. Shinto has been actively involved in research, having completed two projects on Chronic Myeloid Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL) as part of their academic curriculum. His expertise spans the management of benign and malignant hematological disorders, with a primary focus on hemato-oncological diseases such as leukemias, lymphomas, and myelomas, as well as bone marrow transplantation, including haploidentical stem cell transplants.
As part of his commitment to advancing knowledge in cellular therapies, Dr. Shinto received the prestigious Indo-American Cancer Association Fellowship, which enabled him to train in the Stem Cell Department at the MD Anderson Cancer Center, Houston, Texas. He was also awarded the American Society of Hematology Visitor Training Program scholarship, providing opportunities to train in stem cell transplantation at the University Hospitals Seidman Cancer Center and Cleveland Clinic, Ohio. During this time, he gained hands-on experience in CAR T-cell therapy, including cell manufacturing and managing associated complications.
Dr. Shinto has presented numerous papers at national and international conferences and has published in reputed indexed journals. Among their notable accolades is the LEUKA – European School of Hematology International Scholarship, which allowed them to present an oral paper at the 20th Annual John Goldman Conference on Chronic Myeloid Leukemia in Miami, Florida. As the “Young Hematology Scholar Awardee,” Dr. Shinto showcased his work at the 2024 Summit on Hematological Cancers in Nashville, TN, USA, and presented abstracts at the Leukemia, Lymphoma & Myeloma Congress 2024 in New York, USA.
Recently, Dr. Shinto completed an observership at the Mayo Clinic, Rochester, MN, focusing on CAR T-cell and BiTE therapies for multiple myeloma and B-cell malignancies. His exemplary contributions to oncology were recognized with the “Promising Oncologist 2024” award by the TIMES NETWORK.
Currently, Dr. Shinto serves as the Chief & Senior Consultant of the Department of Clinical Hematology, Hemato-Oncology, and Bone Marrow Transplantation (BMT) at Baby Memorial Hospital, Calicut, Kerala, India. With a steadfast commitment to excellence, he aspires to continue advancing the field of hematology, particularly in bone marrow transplantation and cellular therapies, while delivering compassionate and effective care to his patients.
Qualification
- MBBS - Calicut University, Thrissur (Sept 2007)
- MD (Gen Med) - Kerala University of Health & Allied Sciences, Calicut Nov 2013
- DM (Clinical Hematology) - Sanjay Gandhi Post Graduate Institute, Lucknow (June 2017)
- Fellowship in Bone Marrow Transplantation- Rajiv Gandhi Cancer Institute & Research Centre (Jan 2019)
Work Experience
- 2009- June 2009: Medical Officer, PHC Thrikkur, Thrissur, Kerala, India
- June 2013- Jan 2014: Senior Resident, Dept. of General medicine, Govt Medical College, Calicut, Kerala, India.
- Feb 2014- May 2014: Senior Registrar, Dept. of Hematology, Christian Medical College, Vellore, India.
- July 2017 -Aug 2017: Senior Resident, Dept. of Clinical Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
- Oct 2017 – Dec 2017: Attending Consultant, Dept. of Hemato Oncology Jan 2018 - Jan 2019: Fellow in Bone Marrow Transplantation, Dept. of Hemato Oncology and BMTU, Rajiv Gandhi Cancer Institute, Delhi, India.and BMTU, Rajiv Gandhi Cancer Institute, Delhi, India.
- Sept 2018 – Oct 2018: Observership in Stem Cell Transplantation, MD Anderson Cancer Center, Houston, Texas, USA.
- March 2019 – June 2019: American Society of Hematology VTP trainee in Alternative donor stem cell transplantation, University Hospitals Seidman Cancer Center, Cleveland, Ohio.
- July 2019 – Present: Senior Consultant & Chief - Clinical Hematology & Hemato Oncology, Baby Memorial Hospital, Calicut, Kerala, India
- October 2024 – Observer- Department of Hematology/Oncology, Mayo Clinic, Rochester, MN, USA.
Publications
- Thekkudan, S., Ashique, A., & Mariam, H. (2024). Low Dose Venetoclax based Triplet Regimen in Triple Class Refractory t(11:14) Multiple Myeloma. American Journal of Hematology, 99, S3-S64. https://doi.org/10.1002/ajh.27491
- Thekkudan, S., Mariam , H., & Ashique, A. (2024). Rare co-occurrence of BCR-ABL1 fusion, CALR and ZRSR2 mutations In Myeloproliferative Neoplasm. American Journal of Hematology, 99, S3-S64. https://doi.org/10.1002/ajh.27491
- Pillai L, Rabiyabi B, SF Thekkudan, Anoop Kumar; " Acute Promyelocytic Leukemia in Pregnancy Presenting as DIC - A Case Report and Review of Literature." BMH Medical Journal - ISSN 2348–392X [Online], 11.2 (2024): 19-24. Web. 7 Apr. 2024
- Padmanabhan P, Jayameena P, Mampilly N, Francis S, Sherif A, George S, Mathew T; Monoclonal Gammopathy of Renal Significance (MGRS) – Case Series from a Tertiary Center in Kerala. Indian Journal of Nephrology ():10.4103/ijn.ijn_329_22, March 20, 2023.
- Rauf A, Thekkudan SF, Mampilly N, Vijayan A; Childhood-onset systemic lupus erythematosus, probably triggered by severe acute respiratory syndrome coronavirus 2 infection, presenting with autoimmune haemolytic anaemia. Current Medicine Research and Practice 12(5):p 235-237, Sep–Oct 2022. | DOI: 10.4103/cmrp.cmrp_123_21.
- KK A Rauf, M Shanil S Aikot Biju IK S F Thekkudan et al. Decoding the mystery of sky high bililurbin levels in a child with Hereditary Spherocytosis- The Co-existence of Crigler Najjar Syndrome Type 2. BMH Medical Journal - ISSN 2348–392X, [S.l.], v. 9, n. 3, p. 73-76, june 2022. ISSN 2348-392X.
- SS. Pillai, P. A. Ramsheela, R Deepak, S Francis, C. Jayakrishnan, A Praveen, N Mampally; Epidural extension of dorsal vertebral D1–D7 hemangiomas with congenital cutaneous hemangiomas: Case report and literature review. 13-Sep-2021;12:457
- S Manoj, MC Rajesh, A Kacha, S Aikot, R Trivikraman, Thekkudan SF; Anaesthetic Management Of A Patient In Sickle Cell Crisis With Empyema Gall Bladder. BMH Medical Journal, v. 8, n. 1, p. 45-51, oct. 2020.
- Thekkudan SF, de Lima M, Metheny L. Prevention of relapse after allogeneic stem cell transplantation in acute myeloid leukemia: Updates and challenges. Adv Cell Gene Ther. 2019;00:e77. https ://doi.org/10.1002/acg2.77
- Mehta P, Yadav N, Soni P, Thekuddan SF, Singh R, Khushoo V, Mirgh SP, Agrawal N, Ahmed R, Kapoor J, Bhurani D. Experience with Low Dose Thalidomide in Transfusion Dependent Beta Thalassaemia in a Resource Limited Setting; Blood (2019) 134 (Supplement_1): 963.DOI: https://doi.org/10.1182/blood-2019-131682
- Mirgh SP, Kapoor J, Thekuddan SF, Khushoo V, Naim F, Garg A, Agrawal N, Ahmed R, Bhurani D. Combination of Venetoclax and Hypomethylating Agents in Myeloid Malignancies in Patients Unfit for Intensive Chemotherapy - Real World Data from a Tertiary Care Centre in India. Is It Time to Bid Adieu to 3+7? ; Blood (2019) 134 (Supplement_1): 5149. DOI: https://doi.org/10.1182/blood-2019-131746
- Mehta P, Yadav N, Bhaarat M, Mirgh SP, Khushoo V, Thekuddan SF, Agrawal N, Ahmed R, Bhurani D. Carfilzomib-Pomalidomide-Dexamethasone (KPD) in Relapsed/Refractory Multiple Myeloma Patients - an Institutional Retrospective Analysis; Blood (2019) 134 (Supplement_1): 5572. DOI: https://doi.org/10.1182/blood-2019-131674
- Yadav N, Aggarwal M, Mehta P, Kapoor J, Thekkudan SF, Bhandari P, Soni P, Ahmed R, Bhurani D, Agrawal N. Primary Plasma Cell Leukemia: A Retrospective Study of a Rare Disease From Tertiary Cancer Centre From India. Indian J Hematol Blood Transfus (2019) 35: 649.
- Mirgh S, Ahmed R, Agrawal N, Bothra S, Mohan B, Garg A, Thekkudan SF, Khushoo V, Bhurani D. Knowing the Flip Side of the Coin: Ibrutinib Associated Cystoid Macular Edema. Indian J Hematol Blood Transfus (2019). https://doi.org/10.1007/s12288-019-01181-y
- Mirgh S, Ahmed R, Agrawal N, Khushoo V, Garg A, Tejwani N, Singh N, Thekkudan SF, Bhurani D. Will Daratumumab be the next game changer in Early Thymic Precursor-Acute Lymphoblastic Leukaemia? Br J Haematol. 2019 DOI:10.1111/bjh.16154
- Agrawal N, Yadav N, Verma P, Soni P , Mehta P, Thekkudan SF, Ahmed R, Bhurani D; Study of Haploidentical Stem Cell Transplantation for Philadelphia/BCR-ABL Positive Acute Lymphoblastic Leukemia. Indian J Hematol Blood Transfus (2019)
- Ahmed R, Thakur S, Kapoor J, Agrawal N, Mehta P, Thekuddan SF, Garg A, Bhurani D; Incidence of breakthrough invasive fungal infections after Posaconazole prophylaxis in allogenic stem cell transplant patients. Blood (2018) 132 S1:5695
- Agrawal N, Verma P, Yadav N, Ahmed R, Mehta P, Soni P, Francis S, Bhurani D; Outcome of Philadelphia Positive Acute Lymphoblastic Leukemia With or Without Allogeneic Stem Cell Transplantation in a Retrospective Study. Indian J Hematol Blood Transfus (2018)
- S.F. Thekkudan, S. Nityanand, Nilotinib induced avascular necrosis of femoral head in an adult chronic myeloid leukemia patient, J ClinOrthop Trauma (2017)
- Thekkudan SF, Nityanand S; Development of Psoriasis Vulgaris in a Chronic Myeloid Leukemia Patient on Second-Generation Tyrosine Kinase Inhibitor Therapy. J Leuk. 2017 Jun; 5: 229.
- Thekkudan SF, Kumar P, Nityanand S; Voriconazole-induced skeletal fluorosis in an allogenic hematopoietic stem cell transplant recipient. Ann Hematol. 2016 Mar; 95(4): 669-70
- Francis ST, Nair JR, Shiji PV, Mohamed S, Geetha P; A Case Series of Acute Methanol Poisoning from Northern Kerala. Emergency Med 2016 Feb; 6: 312.
Research
- Ikaros deletions in pediatric and adult Indian Acute Lymphoblastic Leukemia
- Impact of Kinase Domain Mutations on Second Line Nilotinib Therapy in Chronic Myeloid Leukemia patients in Chronic Phase- Experience from a tertiary care center in North India
- REACH 3 -A phase III randomized open-label multi-center study of Ruxolitinib vs. best available therapy in patiEnts with corticosteroid-refrACtory chronic graft vs Host disease after allogeneic stem cell transplantation.
Awards & Honors
- Received “Young Hematology Scholar Award” at the 2024 Summit on Hematological Cancers, Nashville,TN, USA.
- Poster presentation at the Leukemia, Lymphoma & Myeloma Congress 2024, New York, USA.
- Poster presentation at the 2024 Summit on Hematological Cancers, Nashville, TN, USA.
- Received “Promising Oncologist 2024” Award by the TIMES NETWORK at the Oncology Conclave 0n 7.6.2024
- Received “American Society of Hematology - VTP Award” for 12 weeks training in Stem cell transplantation and CART therapy at University Hospitals Seidman Cancer Center at Cleveland, Ohio
- Attended as Observer in Stem Cell Transplantation in Cleveland Clinic, Ohio, USA from 20-21 May 2019
- Received “Indo-American Cancer Association Travelling Fellowship” to attend 1-month observer ship in Stem cell Transplantation at MD Anderson Cancer Center, Houston, Texas
- Received “LEUKA-European School of Hematology - International Scholarship” to attend 20th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy, September 2018 at Miami, Florida, USA.
- Selected for Oral presentation at 20th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy, September 2018 at Miami, Florida, USA.
- 2nd Best Poster award at 3rd EHA ISHBT Tutorial conference held at Lucknow, India.
- “The Best Thesis award”2nd prize at the 37th ICON conference held at New Delhi, India.
- “The Best DM Resident” award conferred on the 33rd Annual Foundation day of Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India.
- 2nd Best Poster award for title “Impact of Kinase Domain Mutations on second line Nilotinibtherapy in chronic myeloid leukemia- Experience from a tertiary care center in North India” at 57th HEMATOCON conference held at Jaipur
- 2nd prize in Myeloma-State of the art QUIZ competition at PGIMER, Chandigarh
- 2nd Best poster award for title “Impact of Kinase Domain Mutations on second line Nilotinibtherapy in chronic myeloid leukemia- Experience from a tertiary care center in North India” at ‘BEST OF EHA’ conference held at Mumbai
- "Young ICON Initiative" prize at 31st ICON Conference held at Bhopal, Madhya Pradesh, India - Research grant of Rs.50,000/-
- First prize in Hematology quiz conducted as a part of ‘HEMATOCON’, National CME in Hematology conducted in Calicut, Kerala.
- Second prize in National Hematology quiz [state level] and Third prize [south zone] organized by Indian Society of Hematology and Blood Transfusion (ISHBT).
- First prize in Hypertension quiz organized by Hypertension Society of India as a part of HSICON’ -20th National Conference on Hypertension held at Calicut.
- Silver medal in Obstetrics &Gynecology during MBBS
- Gold medal in Anatomy during MBBS.
Dr. Shinto Francis Thekkudan
Senior Consultant & Chief
OP Days and Timings
- Mon 11:00 AM - 03:30 PM
- Tue 11:00 AM - 03:30 PM
- Wed 11:00 AM - 03:30 PM
- Fri 11:00 AM - 03:30 PM