neurology

Clinical Hematology & Hemato Oncology

Clinical Hematology is branch of clinical medicine which deals with diagnosis and treatment of blood disorders and blood cancers. The department provides tertiary care services for patients with haematological disorders both benign and malignant.

The Department of Clinical Hematology looks after and treats people with blood related disorders. These include blood cancers (Leukemia, Lymphoma, multiple Myeloma), disorders associated with low hemoglobin (various types of anaemia), bleeding disorders (haemophilia and others), and other rare diseases.

  • Acute Leukemia
  • Chronic Leukemia
  • Plasma Cell disorders
  • Lymphoma – Hodgkin / Non Hodgkin
  • Myeloproliferative Neoplasms
  • Thalassemia and other haemoglobinopathies
  • All types of coagulation and thrombotic disorders
  • Haemoglobin and platelet disorders

Panel of Doctors

  • Dr. Shinto Francis Thekkudan

    Senior Consultant & Chief

Tab 1

Dr. Shinto Francis Thekkudan MD (General Medicine), DM (Clinical Hematology), Fellowship in Bone Marrow Transplant

Senior Consultant & Chief

He has worked and got trained at various prestigious institutes across the country like Christian Medical College, Vellore; Sanjay Gandhi Post Graduate Institute, Lucknow and Rajiv Gandhi Cancer Institute, New Delhi. He has vast experience in management of hematological disorders including both benign and malignant conditions. His main areas of interests include hemato-oncological diseases like leukemias, lymphomas and myeloma and also bone marrow transplantation including haploidentical stem cell transplants. He got the Indo-American travelling fellowship and American Society of Hematology scholarship training awards for exposure in Bone Marrow Transplantation at MD Anderson Cancer, Houston, Texas; Cleveland Clinic and University Hospitals-Seidman Cancer Centre, Cleveland, Ohio, USA.

Qualification

  • MBBS - Calicut University, Thrissur (Sept 2007)
  • MD (Gen Med) - Kerala University of Health & Allied Sciences, Calicut Nov 2013
  • DM (Clinical Hematology) - Sanjay Gandhi Post Graduate Institute, Lucknow (June 2017)
  • Fellowship in Bone Marrow Transplantation- Rajiv Gandhi Cancer Institute & Research Centre (Jan 2019)

Work Experience

  • 2009- June 2009: Medical Officer, PHC Thrikkur, Thrissur, Kerala, India
  • June 2013- Jan 2014: Senior Resident, Dept. of General medicine, Govt Medical College, Calicut, Kerala, India.
  • Feb 2014- May 2014: Senior Registrar, Dept. of Hematology, Christian Medical College, Vellore, India.
  • July 2017 -Aug 2017: Senior Resident, Dept. of Clinical Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
  • Oct 2017 – Dec 2017: Attending Consultant, Dept. of Hemato Oncology Jan 2018 - Jan 2019: Fellow in Bone Marrow Transplantation, Dept. of Hemato Oncology and BMTU, Rajiv Gandhi Cancer Institute, Delhi, India.and BMTU, Rajiv Gandhi Cancer Institute, Delhi, India.
  • Sept 2018 – Oct 2018: Observership in Stem Cell Transplantation, MD Anderson Cancer Center, Houston, Texas, USA.
  • March 2019 – June 2019: American Society of Hematology VTP trainee in Alternative donor stem cell transplantation, University Hospitals Seidman Cancer Center, Cleveland, Ohio.

Publications

  • Mirgh S, Ahmed R, Agrawal N, Khushoo V, Garg A, Tejwani N, Singh N, Thekkudan SF, Bhurani D. Will Daratumumab be the next game changer in Early Thymic Precursor-Acute Lymphoblastic Leukaemia? Br J Haematol. 2019 DOI:10.1111/bjh.16154
  • Agrawal N, Yadav N, Verma P, Soni P , Mehta P, Thekkudan SF, Ahmed R, Bhurani D; Study of Haploidentical Stem Cell Transplantation for Philadelphia/BCR-ABL Positive Acute Lymphoblastic Leukemia. Indian J Hematol Blood Transfus (2019)
  • Agrawal N, Verma P, Yadav N, Ahmed R, Mehta P, Soni P, Francis S, Bhurani D; Outcome of Philadelphia Positive Acute Lymphoblastic Leukemia With or Without Allogeneic Stem Cell Transplantation in a Retrospective Study. Indian J Hematol Blood Transfus (2018)
  • S.F. Thekkudan, S. Nityanand, Nilotinib induced avascular necrosis of femoral head in an adult chronic myeloid leukemia patient, J ClinOrthop Trauma (2017)
  • Thekkudan SF, Nityanand S; Development of Psoriasis Vulgaris in a Chronic Myeloid Leukemia Patient on Second-Generation Tyrosine Kinase Inhibitor Therapy. J Leuk. 2017 Jun; 5: 229.
  • Thekkudan SF, Kumar P, Nityanand S; Voriconazole-induced skeletal fluorosis in an allogenic hematopoietic stem cell transplant recipient. Ann Hematol. 2016 Mar; 95(4): 669-70
  • Francis ST, Nair JR, Shiji PV, Mohamed S, Geetha P; A Case Series of Acute Methanol Poisoning from Northern Kerala. Emergency Med 2016 Feb; 6: 312.

Research

  • Ikaros deletions in pediatric and adult Indian Acute Lymphoblastic Leukemia
  • Impact of Kinase Domain Mutations on Second Line Nilotinib Therapy in Chronic Myeloid Leukemia patients in Chronic Phase- Experience from a tertiary care center in North India
  • REACH 3 -A phase III randomized open-label multi-center study of Ruxolitinib vs. best available therapy in patiEnts with corticosteroid-refrACtory chronic graft vs Host disease after allogeneic stem cell transplantation.

Awards

  • Received “American Society of Hematology - VTP Award” for 12 weeks training in Stem cell transplantation and CART therapy at University Hospitals Seidman Cancer Center at Cleveland
  • Attended as Observer in Stem Cell Transplantation in Cleveland Clinic, Ohio, USA from 20-21 May 2019
  • Received “Indo-American Cancer Association Travelling Fellowship” to attend 1-month observer ship in Stem cell Transplantation at MD Anderson Cancer Center, Houston, Texas
  • Received “LEUKA-European School of Hematology - International Scholarship” to attend 20th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy, September 2018 at Miami, Florida, USA.
  • Selected for Oral presentation at 20th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy, September 2018 at Miami, Florida, USA.
  • 2nd Best Poster award at 3rd EHA ISHBT Tutorial conference held at Lucknow, India.
  • “The Best Thesis award”2nd prize at the 37th ICON conference held at New Delhi, India.
  • “The Best DM Resident” award conferred on the 33rd Annual Foundation day of Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India.
  • 2nd Best Poster award for title “Impact of Kinase Domain Mutations on second line Nilotinibtherapy in chronic myeloid leukemia- Experience from a tertiary care center in North India” at 57th HEMATOCON conference held at Jaipur
  • 2nd prize in Myeloma-State of the art QUIZ competition at PGIMER, Chandigarh
  • 2nd Best poster award for title “Impact of Kinase Domain Mutations on second line Nilotinibtherapy in chronic myeloid leukemia- Experience from a tertiary care center in North India” at ‘BEST OF EHA’ conference held at Mumbai
  • "Young ICON Initiative" prize at 31st ICON Conference held at Bhopal, Madhya Pradesh, India - Research grant of Rs.50,000/-
  • First prize in Hematology quiz conducted as a part of ‘HEMATOCON’, National CME in Hematology conducted in Calicut, Kerala.
  • Second prize in National Hematology quiz [state level] and Third prize [south zone] organized by Indian Society of Hematology and Blood Transfusion (ISHBT).
  • First prize in Hypertension quiz organized by Hypertension Society of India as a part of HSICON’ -20th National Conference on Hypertension held at Calicut.
  • Silver medal in Obstetrics &Gynecology during MBBS
  • Gold medal in Anatomy during MBBS.
ummer
Dr. Shinto Francis Thekkudan

Senior Consultant & Chief

OP Days and Timings
  • Mon 11:00 AM - 03:30 PM
  • Tue 11:00 AM - 03:30 PM
  • Wed 11:00 AM - 03:30 PM
  • Fri 11:00 AM - 03:30 PM

Book an Appointment

ummer
Dr. Shinto Francis Thekkudan
Senior Consultant & Chief

He has worked and got trained at various prestigious institutes across the country like Christian Medical College, Vellore; Sanjay Gandhi Post Graduate Institute, Lucknow and Rajiv Gandhi Cancer Institute, New Delhi. He has vast experience in management of hematological disorders including both benign and malignant conditions. His main areas of interests include hemato-oncological diseases like leukemias, lymphomas and myeloma and also bone marrow transplantation including haploidentical stem cell transplants. He got the Indo-American travelling fellowship and American Society of Hematology scholarship training awards for exposure in Bone Marrow Transplantation at MD Anderson Cancer, Houston, Texas; Cleveland Clinic and University Hospitals-Seidman Cancer Centre, Cleveland, Ohio, USA.

  • MBBS - Calicut University, Thrissur (Sept 2007)
  • MD (Gen Med) - Kerala University of Health & Allied Sciences, Calicut Nov 2013
  • DM (Clinical Hematology) - Sanjay Gandhi Post Graduate Institute, Lucknow (June 2017)
  • Fellowship in Bone Marrow Transplantation- Rajiv Gandhi Cancer Institute & Research Centre (Jan 2019)
  • 2009- June 2009: Medical Officer, PHC Thrikkur, Thrissur, Kerala, India
  • June 2013- Jan 2014: Senior Resident, Dept. of General medicine, Govt Medical College, Calicut, Kerala, India.
  • Feb 2014- May 2014: Senior Registrar, Dept. of Hematology, Christian Medical College, Vellore, India.
  • July 2017 -Aug 2017: Senior Resident, Dept. of Clinical Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
  • Oct 2017 – Dec 2017: Attending Consultant, Dept. of Hemato Oncology Jan 2018 - Jan 2019: Fellow in Bone Marrow Transplantation, Dept. of Hemato Oncology and BMTU, Rajiv Gandhi Cancer Institute, Delhi, India.and BMTU, Rajiv Gandhi Cancer Institute, Delhi, India.
  • Sept 2018 – Oct 2018: Observership in Stem Cell Transplantation, MD Anderson Cancer Center, Houston, Texas, USA.
  • March 2019 – June 2019: American Society of Hematology VTP trainee in Alternative donor stem cell transplantation, University Hospitals Seidman Cancer Center, Cleveland, Ohio.
  • Mirgh S, Ahmed R, Agrawal N, Khushoo V, Garg A, Tejwani N, Singh N, Thekkudan SF, Bhurani D. Will Daratumumab be the next game changer in Early Thymic Precursor-Acute Lymphoblastic Leukaemia? Br J Haematol. 2019 DOI:10.1111/bjh.16154
  • Agrawal N, Yadav N, Verma P, Soni P , Mehta P, Thekkudan SF, Ahmed R, Bhurani D; Study of Haploidentical Stem Cell Transplantation for Philadelphia/BCR-ABL Positive Acute Lymphoblastic Leukemia. Indian J Hematol Blood Transfus (2019)
  • Agrawal N, Verma P, Yadav N, Ahmed R, Mehta P, Soni P, Francis S, Bhurani D; Outcome of Philadelphia Positive Acute Lymphoblastic Leukemia With or Without Allogeneic Stem Cell Transplantation in a Retrospective Study. Indian J Hematol Blood Transfus (2018)
  • S.F. Thekkudan, S. Nityanand, Nilotinib induced avascular necrosis of femoral head in an adult chronic myeloid leukemia patient, J ClinOrthop Trauma (2017)
  • Thekkudan SF, Nityanand S; Development of Psoriasis Vulgaris in a Chronic Myeloid Leukemia Patient on Second-Generation Tyrosine Kinase Inhibitor Therapy. J Leuk. 2017 Jun; 5: 229.
  • Thekkudan SF, Kumar P, Nityanand S; Voriconazole-induced skeletal fluorosis in an allogenic hematopoietic stem cell transplant recipient. Ann Hematol. 2016 Mar; 95(4): 669-70
  • Francis ST, Nair JR, Shiji PV, Mohamed S, Geetha P; A Case Series of Acute Methanol Poisoning from Northern Kerala. Emergency Med 2016 Feb; 6: 312.
  • Ikaros deletions in pediatric and adult Indian Acute Lymphoblastic Leukemia
  • Impact of Kinase Domain Mutations on Second Line Nilotinib Therapy in Chronic Myeloid Leukemia patients in Chronic Phase- Experience from a tertiary care center in North India
  • REACH 3 -A phase III randomized open-label multi-center study of Ruxolitinib vs. best available therapy in patiEnts with corticosteroid-refrACtory chronic graft vs Host disease after allogeneic stem cell transplantation.
  • Received “American Society of Hematology - VTP Award” for 12 weeks training in Stem cell transplantation and CART therapy at University Hospitals Seidman Cancer Center at Cleveland
  • Attended as Observer in Stem Cell Transplantation in Cleveland Clinic, Ohio, USA from 20-21 May 2019
  • Received “Indo-American Cancer Association Travelling Fellowship” to attend 1-month observer ship in Stem cell Transplantation at MD Anderson Cancer Center, Houston, Texas
  • Received “LEUKA-European School of Hematology - International Scholarship” to attend 20th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy, September 2018 at Miami, Florida, USA.
  • Selected for Oral presentation at 20th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy, September 2018 at Miami, Florida, USA.
  • 2nd Best Poster award at 3rd EHA ISHBT Tutorial conference held at Lucknow, India.
  • “The Best Thesis award”2nd prize at the 37th ICON conference held at New Delhi, India.
  • “The Best DM Resident” award conferred on the 33rd Annual Foundation day of Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India.
  • 2nd Best Poster award for title “Impact of Kinase Domain Mutations on second line Nilotinibtherapy in chronic myeloid leukemia- Experience from a tertiary care center in North India” at 57th HEMATOCON conference held at Jaipur
  • 2nd prize in Myeloma-State of the art QUIZ competition at PGIMER, Chandigarh
  • 2nd Best poster award for title “Impact of Kinase Domain Mutations on second line Nilotinibtherapy in chronic myeloid leukemia- Experience from a tertiary care center in North India” at ‘BEST OF EHA’ conference held at Mumbai
  • "Young ICON Initiative" prize at 31st ICON Conference held at Bhopal, Madhya Pradesh, India - Research grant of Rs.50,000/-
  • First prize in Hematology quiz conducted as a part of ‘HEMATOCON’, National CME in Hematology conducted in Calicut, Kerala.
  • Second prize in National Hematology quiz [state level] and Third prize [south zone] organized by Indian Society of Hematology and Blood Transfusion (ISHBT).
  • First prize in Hypertension quiz organized by Hypertension Society of India as a part of HSICON’ -20th National Conference on Hypertension held at Calicut.
  • Silver medal in Obstetrics &Gynecology during MBBS
  • Gold medal in Anatomy during MBBS.
OP Days and Timings
  • Mon 11:00 AM - 03:30 PM
  • Tue 11:00 AM - 03:30 PM
  • Wed 11:00 AM - 03:30 PM
  • Fri 11:00 AM - 03:30 PM

Services & Facilities

  • Treatment of all haematological cancers/ disorders like leukaemia, lymphoma, myeloma, MDS, aplastic anaemia, MPD etc.
  • Systemic treatment- chemotherapy, immunotherapy, targeted therapy for all hematological cancers
  • Advice on Stem Cell and bone marrow Transplantation.
  • Dedicated day care chemotherapy unit with all modern facilities like biosafety cabinet
  • Experienced and dedicated nursing staff
  • Provision for inpatient chemotherapy
  • All targeted therapy and immunotherapy
  • Counselling services for cancer patients and relatives
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