neurology

Blood Centre

Transfusion medicine is a multidisciplinary science concerned with the proper use of blood or blood products in the treatment or prevention of disease. Optimal transfusion therapy requires knowledge of blood types and crossmatching procedures, blood sources and donor selection, blood collection and administration techniques, component therapy, transfusion reactions, and red blood cell (RBC) substitutes. Transfusion medicine plays a vital role in the supportive care of patients undergoing hematopoietic stem cell transplantation (HSCT), with a spectrum of applications including donor peripheral blood stem cell (PBSC) collection, cellular processing, granulocyte transfusions, donor lymphocyte infusions, and the evaluation of immunohematologic issues in ABO-mismatched and other transplant situations. Transfusion Medicine Continues to evolve in the Modern Era. The history of transfusion medicine parallels mankind's understanding of physiology, immunology, chemistry, infectious diseases, and advances in technology. What began as a belief that blood carries important healing properties has been validated by science. However, despite numerous advances over the centuries, blood remains an indispensable, life-giving force. Interestingly, some of the more important advances in blood banking/transfusion medicine have occurred as the result of wars.

Panel of Doctors

  • Dr. Jyotis Pothen Raju

    Specialist

Tab 1

Dr. Jyotis Pothen Raju MBBS, MD (Immunohematology & Blood Transfusion)

Specialist

Dr Jyotis Pothen Raju is a specialist in Immunohematology and blood transfusion. He did his MBBS JIPMER, Pondicherry which is an autonomous Institute of National Importance. He finished his post-graduation training from JIPMER, Pondicherry where the Blood Centre has annual collection of more than 12,000 units of blood and around 30-40 Hematopoietic Stem Cell Transplant harvest along with other specialized apheresis procedures. He received training in HLA and Transplant Immunology from CMC, Vellore as part of his post graduate training. He is a skilled and experienced in all practical aspects of Transfusion Medicine. He has special interest in advanced Immunohematological workups of complex cases and apheresis.

Qualifications

  • MBBS – JIPMER, Pondicherry
  • MD (Immunohematology and Blood Transfusion) – JIPMER, Pondicherry

Work Experience

  • Worked as specialist and Blood Centre incharge at Baby Memorial Hospital, Calicut (8 months)
  • Worked as Senior Resident at AIIMS, Mangalagiri (4 months)

Research

  • ‘Evaluation of different methods of elution for the removal of antibodies from red cells in Direct Antiglobulin Test (DAT) positive samples by comparing DAT grade and phenotypic expression of red cell’ under the guidance of Dr Rajendra G Kulkarni, HOD, Department of Transfusion Medicine, JIPMER

Publications

  • Transfusion-associated anxiety: Recognised and overcome in an adolescent child. Accepted and published in Transfusion Clinique et Biologique on May 2021. PMID: 33581309.

Papers Presented

  • Oral paper titled ‘Evaluating three different elution methods (viz. Glycine/HCl EDTA, Heat and Chloroquine diphosphate elution) for removal of antibodies from RBC surface by comparing decrease in DAT grades’ at the XVIII Annual Congress of Asian Association of Transfusion Medicine and 4th Joint meeting of AATM-AABB at New Delhi in December 2023

Other Achievements

  • 2nd place at the National Quiz conducted by SPAN academy at TRANSMEDCON 2022 in Indore, Madhya Pradesh
  • Quizmaster at the ISBTI annual Conference- Kerala chapter at MVR Cancer Centre and Research Institute Kerala, Vellallaserry, Kerala
  • 2nd place in BMT quiz held at JIPMER, Pondicherry
ummer
Dr. Jyotis Pothen Raju

Specialist

ummer
Dr. Jyotis Pothen Raju
Specialist

Dr Jyotis Pothen Raju is a specialist in Immunohematology and blood transfusion. He did his MBBS JIPMER, Pondicherry which is an autonomous Institute of National Importance. He finished his post-graduation training from JIPMER, Pondicherry where the Blood Centre has annual collection of more than 12,000 units of blood and around 30-40 Hematopoietic Stem Cell Transplant harvest along with other specialized apheresis procedures. He received training in HLA and Transplant Immunology from CMC, Vellore as part of his post graduate training. He is a skilled and experienced in all practical aspects of Transfusion Medicine. He has special interest in advanced Immunohematological workups of complex cases and apheresis.

  • MBBS – JIPMER, Pondicherry
  • MD (Immunohematology and Blood Transfusion) – JIPMER, Pondicherry
  • Worked as specialist and Blood Centre incharge at Baby Memorial Hospital, Calicut (8 months)
  • Worked as Senior Resident at AIIMS, Mangalagiri (4 months)
  • ‘Evaluation of different methods of elution for the removal of antibodies from red cells in Direct Antiglobulin Test (DAT) positive samples by comparing DAT grade and phenotypic expression of red cell’ under the guidance of Dr Rajendra G Kulkarni, HOD, Department of Transfusion Medicine, JIPMER
  • Transfusion-associated anxiety: Recognised and overcome in an adolescent child. Accepted and published in Transfusion Clinique et Biologique on May 2021. PMID: 33581309.
  • Oral paper titled ‘Evaluating three different elution methods (viz. Glycine/HCl EDTA, Heat and Chloroquine diphosphate elution) for removal of antibodies from RBC surface by comparing decrease in DAT grades’ at the XVIII Annual Congress of Asian Association of Transfusion Medicine and 4th Joint meeting of AATM-AABB at New Delhi in December 2023
  • 2nd place at the National Quiz conducted by SPAN academy at TRANSMEDCON 2022 in Indore, Madhya Pradesh
  • Quizmaster at the ISBTI annual Conference- Kerala chapter at MVR Cancer Centre and Research Institute Kerala, Vellallaserry, Kerala
  • 2nd place in BMT quiz held at JIPMER, Pondicherry

Services & Facilities

  • Latest Apheresis Technology Available in BMH (Spectra Optia Apheresis System)
  • Donated blood is screened using advanced techniques to ensure high quality and safe components are received by the patients

Procedures

  • Therapeutic Plasma Exchange
    • Guillain Barre Syndrome /AIDP
    • Good Pasture Syndrome/Anti GBM Disease
    • Catastrophic Antiphospholipid syndrome
    • Chronic Inflammatory Demyelinating Polyradiculoneuropathy(CIDP)
    • Hypergammaglobulinemia/Hyperviscosity syndrome
    • Myasthenia Gravis
    • TTP/Thrombotic Thrombocytopenic Purpura
    • Renal Transplant
  • Leukocytapheresis
    • Hyperleukocytosis
  • Platelet Rich Plasma (PRP)
    • Autologous PRP preparation for alopecia, osteoarthritis, epicondylitis, tendinitis etc
  • RBC Exchange
    • Sickle Cell Disease (Acute Stroke, Acute Chest Syndrome,Stroke Prophylaxis, Recurrent pain crisis)
    • Severe Malaria
  • Lipoprotein/ LDL Apheresis
    • Familial Hypercholesterolemia
  • Peripheral Hematopoietic stem cell collection(PBSC)
    • Non-Hodgkin and Hodgkin Lymphoma
    • Multiple Myeloma
    • Severe Aplastic Anemia
    • Acute Leukemia, CML
    • Cryopreservation of stem cells using advanced techniques
  • Donor Lymphocyte Infusion (DLI)
  • Granulocytapheresis
    • Severe Neutropenia unresponsive to antibiotics therapy
    • Chronic granulomatous disease
  • Single Donor Platelet / Single Donor Plasma Collection
  • Thrombocytapheresis
    • Hyperthrombocytosis (Myeloproliferative Neoplasm)
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